Codeine Phosphate 30mg

Codeine Phosphate 30mg, (KOH-deen FOS-fayt) A drug used to treat pain, cough, and diarrhea. It is made from opium or morphine and binds to opioid receptors in the central nervous system. Codeine phosphate is a type of opiate, a type of analgesic agent, a type of antitussive agent, and a type of antidiarrheal agent.

Prior to starting treatment with opioids, a discussion should be held with patients to put in place a strategy for ending treatment with codeine in order to minimize the risk of addiction and drug withdrawal syndrome (see section 4.4).

Long term use – the risk benefit should be assessed regularly by the prescriber.

Codeine should be used at the lowest effective dose for the shortest period of time. This dose may be taken, up to 4 times a day at intervals of not less than 6 hours. Maximum daily dose should not exceed 240mg.

Codeine Phosphate For Cough

Codeine is a naturally occurring alkaloid of opium and internationally the standard weak opioid (World Health Organization 1996). It is metabolized in the liver primarily by glucuronidation,N-demethylation, andO-demethylation. The latter process via cytochrome P450 2D6 is responsible for the transformation to morphine (2–10% of the codeine dose) (Lotsch 2005), the analgesic metabolite of codeine, which itself is devoid of analgesic properties.

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A comprehensive patient history should be taken to document concomitant medications, including over-the-counter medicines and medicines obtained on-line, and past and present medical and psychiatric conditions. Patients may find that treatment is less effective with chronic use and express a need to increase the dose to obtain the same level of pain control as initially experienced. Patients may also supplement their treatment with additional pain relievers. These could be signs that the patient is developing tolerance.

Acetaminophen Codeine Phosphate

The phosphate salt of codeine, a naturally occurring phenanthrene alkaloid and opioid agonist with analgesic, antidiarrheal and antitussive activities

Codeine should be used at the lowest effective dose for the shortest period of time. The dose may be taken, up to 4 times a day at intervals of not less than 6 hours. Maximum daily dose of codeine should not exceed 240mg.

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