Buprenorphine Patch, Buprenorphine buccal film is used to treat pain that is severe enough to require daily, around-the-clock opioid treatment and when other pain medications are ineffective or cannot be tolerated. This medication is not intended to treat slight or infrequent pain.
Transdermal buprenorphine can be used safely for post-operative analgesia and is more effective than oral tramadol in lowering post-operative pain after 24 hours with fewer adverse effects.
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Buprenorphine is a Schedule III opioid with distinct pharmacologic and pharmacokinetic features that contribute to effective analgesia while posing less safety concerns than other opioids. The buccal film formulation is preferred above alternative buprenorphine formulations in terms of bioavailability, safety, and efficacy, according to this review paper. The clinical studies examined here demonstrate that buprenorphine buccal film provides effective and prolonged pain relief that is typically well tolerated, with no reports of respiratory depression in any of the investigations. Clinicians should consider using buprenorphine buccal film as a first-line opioid treatment for chronic pain over other buprenorphine formulations or other opioids based on these clinical findings and individual patient risk/benefit assessments.
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How long does the buprenorphine transdermal system take to work?
Buprenorphine patches may provide pain relief after 24 hours or longer. Other pain medicines, such as acetaminophen and ibuprofen, may be recommended as well.
What are the advantages of buprenorphine treatment?
Buprenorphine, when taken correctly, eliminates withdrawal symptoms and lowers drug cravings without making the user feel high (euphoric) or tired. This reduces the risks associated with opioid usage and allows those addicted to opioids to stabilize their lives.
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Is buprenorphine associated with an increase in blood pressure?
Buprenorphine increased heart rate, dP/dt, and systolic and diastolic blood pressure early and dose-dependently.
What is the classification of buprenorphine?
Buprenorphine is a long-acting (24-72 hour) opioid that causes less respiratory depression than other narcotics at high doses. When buprenorphine is coupled with other central nervous system depressants, particularly benzodiazepines, significant respiratory depression can ensue.